|
|
L-dihydroorotate + NAD+ <=> H+ + Orotate + NADH
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
|
–
|
MK
|
|
BRENDA:
BR36799
KEGG:
R01869
MetaCyc:
OROTATE-REDUCTASE-NADH-RXN
SABIO-RK:
486
|
|
|
|
L-dihydroorotate + NADP+ <=> H+ + Orotate + NADPH
|
1.3.1.15
dihydroorotate dehydrogenase (NADP+)
|
–
|
|
|
BRENDA:
BR36800
KEGG:
R01866
MetaCyc:
OROTATE-REDUCTASE-NADPH-RXN
|
|
|
|
orotidine_5''-phosphate + diphosphate <=> 5-phospho-alpha-D-ribose_1-diphosphate + Orotate
|
2.4.2.10
orotate phosphoribosyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44268
KEGG:
R01870
MetaCyc:
OROPRIBTRANS-RXN
SABIO-RK:
401
|
|
|
|
L-dihydroorotate + fumarate <=> Orotate + succinate
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
MK
|
|
BRENDA:
BR49571
KEGG:
R01867
MetaCyc:
RXN-9929
SABIO-RK:
7103
|
|
|
|
ubiquinone + L-dihydroorotate <=> ubiquinol + Orotate
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS258665;
BS451533
MetaCyc:
RXN0-6491
SABIO-RK:
7221
|
|
|
|
L-dihydroorotate + a_quinone <=> Orotate + a_quinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
K
|
|
BRENDA:
BR48993
KEGG:
R01868
|
|
|
|
L-dihydroorotate + O2 <=> Orotate + H2O2
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS258661
SABIO-RK:
485
|
|
|
|
L-dihydroorotate + ferricyanide <=> Orotate + ferrocyanide
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS258662
SABIO-RK:
11082
|
|
|
|
L-dihydroorotate + acceptor <=> Orotate + reduced_acceptor
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
–
|
|
|
BRENDA:
BS258663
SABIO-RK:
1935
|
|
|
|
L-dihydroorotate + 2,6-dichlorophenolindophenol <=> Orotate + reduced_2,6-dichlorophenolindophenol
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
–
|
|
|
BRENDA:
BS373566;
BS425208
SABIO-RK:
7837
|
|
|
|
L-dihydroorotate + decylubiquinone <=> Orotate + decylubiquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS373569
SABIO-RK:
7836
|
|
|
|
L-dihydroorotate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> Orotate + reduced_coenzyme_Q0
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS373570
SABIO-RK:
11281
|
|
|
|
L-dihydroorotate + menadione <=> Orotate + menadiol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS398293
SABIO-RK:
10097
|
|
|
|
L-dihydroorotate + FMN <=> Orotate + FMNH2
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS413428
SABIO-RK:
10404
|
|
|
|
electron-transfer_quinone + L-dihydroorotate <=> electron-transfer_quinol + Orotate
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
M
|
|
MetaCyc:
DIHYDROOROTATE-DEHYDROGENASE-RXN
|
|
|
|
Orotate + H+ + e- <=> L-dihydroorotate
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-6490
|
|
|
|
L-dihydroorotate + menaquinone <=> Orotate + menaquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
MetaCyc:
RXN0-6554
|
|
|
|
H+ + Orotate <=> H+ + Orotate
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-121C
|
|
|
|
dihydroorotate + O2 <=> Orotate + H2O2
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
B
|
|
BRENDA:
BS373091
|
|
|
|
dihydroorotate + 2,6-dichlorophenolindophenol <=> Orotate + reduced_2,6-dichlorophenolindophenol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS373082
|
|
|
|
dihydroorotate + ferricyanide <=> Orotate + ferrocyanide
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS373088
|
|
|
|
Orotate + ferricyanide <=> L-dihydroorotate + ferrocyanide
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS374104
|
|
|
|
Orotidine + diphosphate <=> Orotate + alpha-D-ribose_1-diphosphate
|
2.4.2.10
orotate phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS423914
|
|
|
|
dihydroorotate + menadione <=> Orotate + menadiol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373090
|
|
|
|
L-dihydroorotate + menadione <=> Orotate + 2-Hydroxy-1,4-naphthoquinone
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373573
|
|
|
|
dihydroorotate + ubiquinone <=> Orotate + ubiquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
|
|
|
BRENDA:
BS373083
|
|
|
|
Orotate <=> Uracil + CO2
|
4.1.1.23
orotidine-5'-phosphate decarboxylase
|
–
|
|
|
BRENDA:
BS445772
|
|
|
|
dihydroorotate + NAD+ <=> Orotate + NADH + H+
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
|
–
|
B
|
|
BRENDA:
BS370137
|
|
|
|
dihydroorotate + fumarate <=> Orotate + succinate
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS388543
|
|
|
|
L-dihydroorotate + ubiquinone-30 <=> Orotate + ubiquinol-30
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS425209
|
|
|
|
L-dihydroorotate + 2,5-dimethyl-4-benzoquinone <=> Orotate + 2,5-dimethyl-1,4-benzoquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS425206
|
|
|
|
L-dihydroorotate + coenzyme_Q10 <=> Orotate + Ubiquinol-50
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS425210
|
|
|
|
L-dihydroorotate + coenzyme_Q10 <=> Orotate + reduced_coenzyme_Q
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS438035
|
|
|
|
L-dihydroorotate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> Orotate + ubiquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS451532
|
|
|
|
L-dihydroorotate + crotonate <=> Orotate + Butyrate
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS397568
|
|
|
|
L-dihydroorotate + mesaconate <=> Orotate + 2-methylbutanedioic_aicd
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
|
BRENDA:
BS397571
|
|
|
|
L-dihydroorotate + coenzyme_Q7 <=> Orotate + reduced_coenzyme_Q7
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS451534
|
|
|
|
L-dihydroorotate + 2,6-dihydrophenolindophenol <=> Orotate + reduced_2,6-dihydrophenolindophenol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS453881
|
|
|
|
L-dihydroorotate + ubiquinone-6 <=> Orotate + ubiquinol-6
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373572
|
|
|
|
L-dihydroorotate + ubiquinone-4 <=> Orotate + reduced_ubiquinone-4
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373571
|
|
|
|
L-dihydroorotate + 2,6-dihydroindophenol <=> Orotate + reduced_2,6-dihydrophenolindophenol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS451530
|
|
|
|
L-dihydroorotate + 1,4-Naphthoquinone <=> Orotate + 1,4-naphthoquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS425204
|
|
|
|
dihydroorotate + K3Fe(CN)6 <=> Orotate + K4[Fe(CN)6]
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS388544
|
|
|
|
dihydroorotate + ubiquinone-30 <=> Orotate + ubiquinol-30
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS388545
|
|
|
|
dihydroorotate + 2,5-dimethyl-4-benzoquinone <=> Orotate + 2,5-dimethyl-1,4-benzoquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373080
|
|
|
|
dihydroorotate + 2,5-dimethyl-4-benzoquinone <=> Orotate + reduced_2,5-dimethyl-p-benzoquinone
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373079
|
|
|
|
dihydroorotate + coenzyme_Q10 <=> Orotate + reduced_coenzyme_Q
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS404998
|
|
|
|
dihydroorotate + coenzyme_Q10 <=> Orotate + reduced_ubiquinone-50
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373097
|
|
|
|
dihydroorotate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> Orotate + reduced_2,3-dimethoxy-5-methyl-1,4-benzoquinone
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS388540
|
|
|
|
dihydroorotate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> Orotate + reduced_CoQo
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373084
|
|
|
|
dihydroorotate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> Orotate + reduced_coenzyme_Q0
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373093
|
|
|
|
dihydroorotate + Ubiquinone-10 <=> Orotate + reduced_coenzyme_Q
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373095
|
|
|
|
dihydroorotate + decyl-plastoquinone <=> Orotate + decyl-plastoquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373085
|
|
|
|
dihydroorotate + decylubiquinone <=> Orotate + decylubiquinol
|
1.3.5.2
dihydroorotate dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS373087
|
|
|
|
dihydroorotate + acceptor <=> Orotate + reduced_acceptor
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
1.3.5.2
dihydroorotate dehydrogenase (quinone)
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
–
–
|
|
|
BRENDA:
BS258769
|
|